4-4 cell — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T21679	4'-bromo-Resveratrol		Sirtuin
	4'-bromo-Resveratrolis a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3)		Sirtuin
T7799	BMP signaling agonist sb4	SB 4	TGF-beta/Smad
	BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)		TGF-beta/Smad
T26889	Borofalan(10B)	L-4-Boronophenylalanine	Others
	Borofalan(10B) (L-4-Boronophenylalanine) echibits antineoplastic effects. Borofalan can be used in studies on recurrent or locally advanced head and neck cancer.		Others
T8490	Butoconazole	1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole	Antifungal
	Butoconazole (1-[4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole) is an imidazole antifungal agent		Antifungal
T0125	Epirubicin hydrochloride	Pharmorubicin,4'-epidoxorubicin HCl,Epirubicin HCl,4'-Epidoxorubicin hydrochloride	Apoptosis , DNA/RNA Synthesis , Topoisomerase
	Epirubicin hydrochloride (Pharmorubicin) is an antineoplastic agent which can inhibit Topoisomerase.		Apoptosis , DNA/RNA Synthesis , Topoisomerase
T3189	B7/CD28 interaction inhibitor 1	CTLA-4 inhibitor	Others
	B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor.		Others
T24984	5J-4		Calcium Channel
	5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE). 5J-4 reduces the production of IL-17 and decreases the expression of RORα and RORγt.		Calcium Channel
T2A2476	L-Hydroxyproline	trans-4-Hydroxy-L-proline,L-Hydroxyprolin,Trans-4-Hydroxyproline	Endogenous Metabolite
	L-Hydroxyproline (L-Hydroxyprolin) is one of the hydroxyproline (Hyp) isomers. L-Hydroxyproline is a useful chiral building block in the production of many pharmaceuticals.		Endogenous Metabolite
PDK0101	4-Methylcinnamic acid		Antifungal
	4-Methylcinnamic acid is a cinnamic acid analog that can be used as an intervention catalyst to overcome antifungal tolerance. 4-Methylcinnamic acid can improve the potency of cell wall-disrupting agents.		Antifungal
T0314	Hexylresorcinol	4-Hexylresorcinol	Apoptosis , Tyrosinase , Antibacterial , Parasite
	Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.		Apoptosis , Tyrosinase , Antibacterial , Parasite
T0830	Bithionol	Actamer	cAMP , Parasite
	Bithionol (Actamer), formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bit...		cAMP , Parasite
T5080	Spermidine trihydrochloride	Spermidine hydrochloride,4-Azaoctamethylenediamine trihydrochloride	NMDAR , Autophagy
	Spermidine trihydrochloride (4-Azaoctamethylenediamine trihydrochloride), a natural polyamine, is a novel autophagy inducer and negatively modulates N-methyl-d-aspartate (NMDA).		NMDAR , Autophagy
T8211	(±)-Decursinol	3',4'-dihydro-3'-hydroxy-Xanthyletin	Others , Antibacterial
	(±)-Decursinol (3',4'-dihydro-3'-hydroxy-Xanthyletin) is a natural product from Angelica gigas.		Others , Antibacterial
T9628	10074-A4		c-Myc
	10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from that of a non-binding ligand.		c-Myc
T8656	CAY10404	3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T	Apoptosis , Akt , COX
	CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSC-LC cel...		Apoptosis , Akt , COX
T4893	Spermidine	N-(3-Aminopropyl)-1,4-diaminobutane,N-(4-Aminobutyl)-1,3-diaminopropane	Endogenous Metabolite
	Spermidine (N-(3-Aminopropyl)-1,4-diaminobutane) inhibits NOS1 (nNOS). Spermidine binds and precipitates DNA and may be used for purification of DNA binding proteins. Spermidine activates PNK (polynucleotide kinase T4). ...		Endogenous Metabolite
TP1328	TB500		Others
	TB-500 is a synthesised peptide, essentially a short-chain version of the naturally occurring Thymosin Beta-4.		Others
T2437	O4I2	O-4I2,O4I2	OCT
	O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.		OCT
TN1727	Helichrysetin		Apoptosis , HIV Protease
	Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.		Apoptosis , HIV Protease
T2S0820	Karanjin		Apoptosis , AMPK
	Karanjin is a flavonoid obtained from the seeds of the karanja tree.Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arre...		Apoptosis , AMPK